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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d3753008ec83001c8cc0fd98e645189b8fc57dd8df2c5ac08b90e9093fc6366' 
  AND token = 'a+ypfIbO304L+iLNkF8AmFNjynjG5cWzKG/q6dLnkDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}