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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1115d23b2fea798a9c5040a2af1e556b7c0b0c1c6022c58c586bff78380bdd02' 
  AND token = 'D5/D3tSv7x5psI6TXn4sgq57AsKoPNPKAwNItDb1PYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}