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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a879cb85b54948661b8d80cd71af5d8e7fa6cf8ce3379343cbac3dc840be6645' 
  AND token = '2jIQCYCCBQ6U43HH2TywD37cKogYc3foWqlVR1gm9WI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}