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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c12f4a927c7349b967a2f301f4aab000b5a10e3ff9df0609b864e14c38167cc7' 
  AND token = 'EC9X5zwNN+X3gelLMC8QREL4mkzbcXFxA3n/sGAw3Ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}