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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fb09aa0b05788b91b881075903a1ce508a629e5f67bed6fc21d7cb3c74bfbc3' 
  AND token = 'T1qLF/sYIfeL4w96jYrN/oU2DoINBmuhDtNuYYaDLTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}