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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2ff605b10ddad785b70f52e81e4eb45ab13ad017afce084550c83f28784b283' 
  AND token = 'CYCM12228jlTPpJa7GPtJ0rPFzODgw8zoqrCokL5moM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}