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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '126ae99244c41dbc2f1430eb398ba231e081335c33f4c9aa8fab51ddd8697b48' 
  AND token = 'Yt/ptSSY1WmAAc9CFksEk8ubpwcIAkFNmAxbreQtunQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}