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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19c9d6f3e30ee82e6189ce71b50d3002c7f077c72007ab61895b1f7ec60ea948' 
  AND token = 'jtdwEw1ckk7s6Fx2rtUYnsUNs5n6nDgvOB92vs7TcVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}