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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15591cc1888af8345d156e015af12931e5c615acf75f752ebf34e2154c47acca' 
  AND token = 'XnPh1tsrF7ZlgrN/i4AtLsPwm7vM962KTw9T/wBRTng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}