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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '777973651c8b86607f4f29f4a2f53e2e783b118f9c0f116db634effa59de8e9c' 
  AND token = 'TEuf8n6zAPbaYynZ7XPq5wbhO06LsrRoZ48cNaLdK9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}