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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66ce7d3ca71c71a2071f8b653135fba98df2007c78e2776f5eeb4fe3378940a9' 
  AND token = '35edaxt/2se+8GjZE34YXAIry9dH2AzYQztjXkdukho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}