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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc4b020a5637479cde0b1f5926e7686afa52e51c9540b683dfeef23cad79dd2b' 
  AND token = 'WYLho3FiMScf7VX9ONoHM90pmTmLomyghg+6xshV2kU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}