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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc06c3f320cf867d60080f070ebb89106a5309b6f7d1898e3fb67cdec63b0393' 
  AND token = 'jlRd2BtWgOtvDqqjDpdHVK6zM7TVASgh6nyt1ELzaPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}