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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72cbd8bc41b18354ba45e69bcef009a8fe3be0d2e87e960d4417a2aee7b9b180' 
  AND token = '4rcKkquCUi7MaZK6JgTfuz69h8bHKzXG7puCw+UiBy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}