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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e7eb457a40ea1b31123b75196557fbf7f8034314da6d0b64cf026851ce8cbce' 
  AND token = 'eKokVaOkOEEMiT3VeRSUiCs7WSQM18Q/Zp21X6bWC10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}