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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46694e9af3fb51eb61411477a011d4b7f8b633e52d582af6a8875eb98457300b' 
  AND token = 'fo9guMJFVZPdex36FhUlr3P7RrIAgfqL426lPAWhsMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}