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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d38b79095ed057f55e542040f43d182e830a99d8c9e1e90a853f23157a14b4c' 
  AND token = 'bUMmRNVG2kjvPbAyGBiOYnRqM5sC1d+ttorsO8g7PCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}