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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dc8e15f83acfe809eea78eafdbcf315f90ef4a3414fc24b41e45f4ddc60a17b' 
  AND token = 'YM/WVOWiC67FKutxrcE8v1RhX4Aw2VEMOsOfRXLfSys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}