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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77dfc343e4cc5370583b866fd4d8d0ee7bac425dcc0cacfc5f19b66e6b98cde3' 
  AND token = 'LZxmXNCPf1NSIrj3u+szMmfZLFkf9iXv9jSEc9M0Prs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}