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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a3a38386a1e13860d55a5ba7154c8ec32819bb38456ff648121c6b0124f2255' 
  AND token = 'RCYxo0u1h+b8Y/AzY3jXVf9264txIu57QN80rOIgXM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}