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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ade2c0c5eeeda5a65f5d99e8a7b887d97cf29541d7f6e0332d2888e02281436' 
  AND token = '2G/ULORDP8iayIK7FgSizra/N8padTzjy8XYPZNVY2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}