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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43957df7d872a0161131cbab6305617fc7c0a104a0ec0b2b88603575edd2486c' 
  AND token = 'qPjnieiQCuBhcpN87XtQf34nB6dTZXwvlWBCsw4OApk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}