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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4db48f65e8cf3a8f1f2aa48c22a4501907e9f542b2ad71f49ced5f37719349c6' 
  AND token = '8tpDjMKc1WUiQXk7kh0p3gAedKCQDOJW4klA5yEQyR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}