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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c4f97fa51654e4ec33dccc2429fbb997772bc0627e5c65c0aed5aea7aba470f' 
  AND token = 'xA0gJXY+YnAPxeLNEPuc62pBBUsSNt/yso4+GoeWLXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}