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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f317f599e2833eea4bd6537045da7e130d6c0b00d09b16e551b509fd3843d4f0' 
  AND token = 'AzLoRecneKctf3Mvse/MfyUgtIWP15+gQ7oAGtzEBeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}