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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e7d83e69d1887c19775097712ad33653866977b40eba7844bd6c67e45249e1f' 
  AND token = 'ZDedj/odcrqwIN4qR1f47fTRkjvbE6l9ryS3wPBc0v0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}