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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e584d993c5f70b1a98f91efdc255837be00c3a1b0f12ca9661237a0c718a9023' 
  AND token = 'yWgexcW3kO/fw3fgCE4Q36NTdlxR4Z3sxpl1JeCn52I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}