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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3537a397167bee107324e2c07a8303d7322217049e93e193dd81b7518de46101' 
  AND token = '8JrX5hbBzA9IpdrJZgBPcyxJS0YEZhMOFNqzIkSN7zU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}