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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cb15a459969b070396a8a859ccc756e3183abb036b1fed760325831b1e7ea68' 
  AND token = '5SY6CaBMV56epa/mnJG2rHqQ1o3Y8UTeeM5R3UId3QY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}