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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13ac41f7f28fdc9f046bef6b31771d51a35374e3c19da7bce80b44ab0b8642c0' 
  AND token = 'hkpX2VOYy+wGjlfUFXyNYNJ+ar4MRmMKYeEWr6m/KaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}