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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cc8f9d370d1d8bd39067ed725290d2aa5249ab8f6f7b208fd8303a544457834' 
  AND token = '3Fik9GpkrcY3fSRwtH6TKTawy45D5CHAsl5AGE2dcjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}