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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d4c6fbad46a5d03f15c7932336cc81004cb58b650d949313ea21304b1a3827f' 
  AND token = 'NxKJvjrd5BEGMf8HlIGH/NWBQnbJtTXEhAW89ro/rTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}