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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1b6ead78b3eeaa1f5b887e192604ab35c4dacd4ad2100b9561d96ea96b91e41' 
  AND token = 'uY88hiSB9AJFYKnkZDLYQV6z2Zpm3BjLjzdsOsWjDU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}