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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d2b826c6f4a7afe9d5828028b41433436623cfa6e8fa0877340a076ee3d20e' 
  AND token = 'u0+auqe5UG9enRunxrse9im5trJJqOjsQboicRzJ+xE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}