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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d45258ce0d444cbb62915108880e44560c12987cd22a0f682fc50f987c708e6' 
  AND token = '7A/VlZfZ++rGDyFI6I2ZmxikE6GkM8FFacoRIbtHxSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}