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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d8d7ed950689da849069ae672e26bf9c6a500ded4dd531ee2b1cfdb21c7d749' 
  AND token = 'uMrcG8m9Q3M18B5nA8RgTUKGqpidhqcwz1q049RM3WI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}