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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad4e7572135e506295eed0d0bf44f0015bff90d1f67dd7359e4623760f5cfd4' 
  AND token = '8FTjmSPBOhAusGUeqD7HXBH4bVI4wcoMRuwPpAwSYRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}