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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5259ef117fb98f93c4875742f1cd9642b2f9a735f204e2789320738748fc475d' 
  AND token = 'zyuiuO/v+JbzoTG8+zkKjvbx2TEIcrxMoM14CZDKP28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}