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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53a4dfc743a144adfd18d914ede50e105afcd540365413f3836c7c2b1a92eb31' 
  AND token = 'zY7jE+fkzP70CwdVqg/mac2+wgDPfhys7wsWyBOcHkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}