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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a34feb6f935ba33864018050658bb5a94e936cfd6b22e2d0fe933dbf5d3a5428' 
  AND token = 'CPyfXrQ+GtIaZbtXO58e0pfDMbRvAv5yzp+E8OuRt5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}