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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be511e1b35193e5e1594e40ea332ad28cc9cd2a2b28bf56652732cb60a70e255' 
  AND token = 'HsPgvP2iq2kOXXASW59ZaG+2fzpiKS9EQiwUoZRoWdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}