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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a1af1cf85ebc8cbe7f274bb7ce0a42f896352d9820eba820f6c02d7ff665b37' 
  AND token = 'UX2XOS5PA3hDZjuSXgYSJxm8Gx8peDyiJ4i14tW4vGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}