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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25ab0c4b3a5b0d9e44f4a70fce267d957d3e04faeee4716956dbc817f5e93775' 
  AND token = 'q6eFVz2YzAw83Xy19QiRvoIQwPIzS4C/XrJ2N04dTEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}