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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '265e9e21afee4069f85eccd23821ee9e3086b335700906ad32c7863cb554383d' 
  AND token = 'D6TppD59b7Teiu8Iog8L9UDlP+y2XTYZ2ohow/fXFGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}