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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4db4e42070416e61f5df3b150a9742bc1f4f7c9111418d30cc6ed17307809c60' 
  AND token = 'Mz9j1U14ony4ipXkEN14c0Qm5wyUw7xCLv/2Ety3z5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}