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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b50c4499ab15c079a649722e244c89d41231b504a7fa8f1cfc40dc0547372c1d' 
  AND token = 'yxPK4zXH1fh4mzCGye9G+1yNqtQtndYmrvFkkY4zYvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}