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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6156a5081e2db3f8e6c658651065862f962ac2761c3fd13dbb6eabc4c6a572d6' 
  AND token = 'f6+kf7fLVWaAEMjJxvlkQBp5qmwSAkwD+vcJkjgm5w4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}