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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '227575214819b92009d70956f6e8ff6789c098d2678eee135cfd98c2d1ee7863' 
  AND token = '3di7Hgm2T05N6OiKFSqDkBwVarQTywe5xrLIlVw1SVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}