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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b0bae895836b87af52d27f3d3fd2165678f6c41c26df199a994996c6d357d75' 
  AND token = 'AONM7cv8nB2IFufMEGaILa6s0K+NYrxRzilqrxfHeJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}