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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b8ef2193d6718fffea30cf34ee15662ce5c864d735cb375fa1640cabb3fd4cc' 
  AND token = 'pVggLHACGsiDmZICyu6Yn1n4lO8Lmb7MQJJGhoIT60Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}